<p>Red oval, genes up-regulated in both STZ and NOD diabetic mouse model oocytes; orange oval, genes up-regulated in STZ diabetic oocytes; green oval, genes down-regulated in NOD diabetic oocytes; blue oval, genes down-regulated in both STZ and NOD diabetic oocytes. Adpgk, ADP-dependent glucokinase; Fbp1, fructose bisphosphatase; Pfkl, phosphofructokinase, liver, B-type; and Bpgm, 2,3-bisphosphoglycerate mutase.</p
Diabetes is a global health problem caused primarily by the inability of pancreatic beta-cells to se...
Obesity is the main cause of type 2 diabetes, accounting for 90-95% of all diabetes cases in the US....
<p>[A] Abnormal mitochondrial metabolism in HFD denuded GV oocytes. A. Individual oocytes were assay...
<p>Red, genes up-regulated in both STZ and NOD diabetic mouse oocytes; Blue, genes down-regulated in...
In mouse ovarian follicles, granulosa cells but not oocytes take up glucose to provide the oocyte wi...
<div><p>In mouse ovarian follicles, granulosa cells but not oocytes take up glucose to provide the o...
<p>(A, D) Schematic of gluconeogenesis, glycolysis and glycogen metabolism, and the expression of en...
Background: Type I diabetes is a global public health concern that affects young people of reproduct...
In the present study, we have utilized a streptozotocin-in-duced diabetic mouse model to examine how...
(A) The diabetic mouse ovaries showed strong C3A, FAS, FASL t-BID and BAX expression in the granulos...
<p>(<b>A</b>) Schematic illustration of the experimental procedure. (<b>B</b>) Statistics of transcr...
Diabetes mellitus (DM) is a chronic disease that affects nearly 10% of the population worldwide. The...
The onset and progression of diabetes mellitus type 2 is highly contingent on the amount of function...
Emerging evidence has shown that oocytes from diabetic ovaries exhibit delayed maturation, mitochond...
A key aspect of glucose homeostasis is the constant monitoring of blood glucose concentrations by sp...
Diabetes is a global health problem caused primarily by the inability of pancreatic beta-cells to se...
Obesity is the main cause of type 2 diabetes, accounting for 90-95% of all diabetes cases in the US....
<p>[A] Abnormal mitochondrial metabolism in HFD denuded GV oocytes. A. Individual oocytes were assay...
<p>Red, genes up-regulated in both STZ and NOD diabetic mouse oocytes; Blue, genes down-regulated in...
In mouse ovarian follicles, granulosa cells but not oocytes take up glucose to provide the oocyte wi...
<div><p>In mouse ovarian follicles, granulosa cells but not oocytes take up glucose to provide the o...
<p>(A, D) Schematic of gluconeogenesis, glycolysis and glycogen metabolism, and the expression of en...
Background: Type I diabetes is a global public health concern that affects young people of reproduct...
In the present study, we have utilized a streptozotocin-in-duced diabetic mouse model to examine how...
(A) The diabetic mouse ovaries showed strong C3A, FAS, FASL t-BID and BAX expression in the granulos...
<p>(<b>A</b>) Schematic illustration of the experimental procedure. (<b>B</b>) Statistics of transcr...
Diabetes mellitus (DM) is a chronic disease that affects nearly 10% of the population worldwide. The...
The onset and progression of diabetes mellitus type 2 is highly contingent on the amount of function...
Emerging evidence has shown that oocytes from diabetic ovaries exhibit delayed maturation, mitochond...
A key aspect of glucose homeostasis is the constant monitoring of blood glucose concentrations by sp...
Diabetes is a global health problem caused primarily by the inability of pancreatic beta-cells to se...
Obesity is the main cause of type 2 diabetes, accounting for 90-95% of all diabetes cases in the US....
<p>[A] Abnormal mitochondrial metabolism in HFD denuded GV oocytes. A. Individual oocytes were assay...