<p>Spontaneous epileptic seizures were exclusively observed in BDV-infected transgenic animals and appeared more frequently in homozygous transgenic BDV-infected mice starting 21 dpi. Seizures were first noted 42 dpi in heterozygous transgenic animals. dpi: days post infection, –/–: non-transgenic mice, Tg/–: heterozygous transgenic mice, Tg/Tg: homozygous transgenic mice</p
<p>After BDV-infection TNFR1 mRNA levels increased significantly in transgenic mice, mainly in the b...
<p>After BDV-infection TNFR2 mRNA levels increased significantly in the transgenic mice, mainly in t...
Proinflammatory state of the brain increases the risk for seizure development. Neonatal Borna diseas...
<p>Microglia increased significantly only in the TNF-transgenic BDV-infected mice starting 21 dpi. E...
<p>Wild-type mice showed a mild immune cell infiltration without progression during the investigatio...
<p>A–F Hematoxylin and eosin staining: Mild inflammatory reaction and no microglia activation in non...
<p>TNFtg mRNA was present only in the transgenic animals. TNFtg mRNA copy numbers were significantly...
<p>After 21 dpi, the viral nucleoprotein BDV-N showed a disseminated and comparable distribution in ...
In conclusion, we have discussed a reverse genetics approach to studying seizure disorders in mice (...
<p>(A) Seizure severity score of 1.5, 3 and 6 month-old Tg2576 male mice and non-transgenic (NTg) ag...
Epilepsy is one of the most common but genetically complex neurological disorders in humans. Identif...
Olfactory bulb kindling rates were studied in two inbred strains of genetically seizure-prone mice (...
<p>TNFto mRNA values were significantly higher in transgenic mice and consisted of approximately 50%...
The recombinant inbred mouse strain, SWXL-4, exhibits tonic-clonic and generalized seizures similar ...
AbstractMice transgenic with the human poliovirus receptor gene develop clinical signs and neuropath...
<p>After BDV-infection TNFR1 mRNA levels increased significantly in transgenic mice, mainly in the b...
<p>After BDV-infection TNFR2 mRNA levels increased significantly in the transgenic mice, mainly in t...
Proinflammatory state of the brain increases the risk for seizure development. Neonatal Borna diseas...
<p>Microglia increased significantly only in the TNF-transgenic BDV-infected mice starting 21 dpi. E...
<p>Wild-type mice showed a mild immune cell infiltration without progression during the investigatio...
<p>A–F Hematoxylin and eosin staining: Mild inflammatory reaction and no microglia activation in non...
<p>TNFtg mRNA was present only in the transgenic animals. TNFtg mRNA copy numbers were significantly...
<p>After 21 dpi, the viral nucleoprotein BDV-N showed a disseminated and comparable distribution in ...
In conclusion, we have discussed a reverse genetics approach to studying seizure disorders in mice (...
<p>(A) Seizure severity score of 1.5, 3 and 6 month-old Tg2576 male mice and non-transgenic (NTg) ag...
Epilepsy is one of the most common but genetically complex neurological disorders in humans. Identif...
Olfactory bulb kindling rates were studied in two inbred strains of genetically seizure-prone mice (...
<p>TNFto mRNA values were significantly higher in transgenic mice and consisted of approximately 50%...
The recombinant inbred mouse strain, SWXL-4, exhibits tonic-clonic and generalized seizures similar ...
AbstractMice transgenic with the human poliovirus receptor gene develop clinical signs and neuropath...
<p>After BDV-infection TNFR1 mRNA levels increased significantly in transgenic mice, mainly in the b...
<p>After BDV-infection TNFR2 mRNA levels increased significantly in the transgenic mice, mainly in t...
Proinflammatory state of the brain increases the risk for seizure development. Neonatal Borna diseas...