Decreased inflammatory responses after treatment with CII pulsed T/C-DC in CIA mice.

<p>A) IgG2a and IgG1 production against CII and <i>Mycobateria tuberculosis</i> were measured by ELISA in the sera from differentially treated DC recipient mice on day 35 of onset. Data are representative of two independent experiments. Values show the mean ± SD of optical density at 450 nm (OD450) of 5 mice per group. B) IL-17, IFN-γ, IL-4, IL-10 and TGF-β levels were detected by ELISA in the supernatant of cultures of DLN cells from mice on day 10 of onset stimulated with or without CII for 48 h. C) IL-17 and IFN-γ were measured by ELISA in joint homogenate. Data are representative of three independent experiments. Values are the mean ± SD. *<i>P</i><0.05, **<i>P</i><0.005 versus PBS group in A, B and C.