Costimulatory molecule expression on cDCs during chronic infection.

<p>(<b>A</b>) Splenic cDCs were gated as MHCII^hiCD11c^hi cells (top panel) and further gated into the three major subsets based on CD4 and CD8α expression (bottom panel). (<b>B</b>) Surface expression of CD40, CD80, CD86 and PD-L1 on the entire cDC population. (<b>C–F</b>) Surface expression of CD40 (C), CD80 (D), CD86 (E) and PD-L1 (F) by each cDC subset. Data are expressed as mean fold change ± SEM of the MFI on cDCs from infected mice compared to naïve mice (n = 4 mice per group). Data is representative of 3 experiments.