miR-182 downregulates the expression of MITF and c-Met.

<p>(A) MITF expression in M23 and SP6.5 cells after transfection with miR-182 was dramatically reduced by Western blot analysis. GAPDH was used as an internal control. (B) c-Met expression in M23 and SP6.5 cells after transfection with miR-182 was dramatically reduced by Western blot analysis. GAPDH was used as an internal control. (C) miR-182 downregulated expression of p-Akt and p-ERK1/2, but not total Akt or ERK1/2. M23 and SP6.5 cells were either mock, transfected with a negative control or miR-182, lysed, and then used for Western blot analysis.