TSA retards the tumor growth NQO1 dependently in A549 tumor xenografted nude mice.

<p>A, upper, tumor volume measurement (P<0.01, TSA vs. control; P<0.05, TSA vs. TSA+DIC); lower, tumor weight (# P<0.05, TSA vs. TSA+DIC, *** P<0.001, TSA vs. control); data are shown as mean ± SE of six mice. B, histological examinations; tumor and tissue sections were analyzed by hematoxylin and eosin staining for histological features. C, biodistribution of TSA in A549 tumor loaded nude mice; data are shown as mean ± SE of 6 mice.