Schematic of the genomic island containing LEE.

<p>The extent of the genomic island is marked by the solid gray line and the bounding genomic genes outside the genomic island are marked in yellow. Genes that are not part of the LEE region are marked in grey. Genes that form the T3SS are shown in green, the <i>pheV</i> tRNA insertion point is marked by a small red arrow with the remainder of the LEE region in blue. Redundant text from the locus tags has been removed to simplify the figure. The full locus tag of those genes designated with a 4 digit number would read SESS1296_0XXXX. The operon structure of the LEE region is indicated by black arrows. Gene functions are abbreviated, putative integrase (INT), putative transcriptional regulator (TR), putative secreted effector (SE). Groups of genes for which homologs co-occur in other organisms are indicated by curly brackets. Possible pseudogenes are marked with (*). G+C content calculated with a 100 bp window is depicted by the graph below the diagram with maximum (upper line = 61%) and minimum (lower line = 24%) values designated. Typical G+C content of 52% for <i>Salmonella</i> genomes is depicted by the dashed red line. Four tandem repeat regions are depicted by small red boxes. A plot of genetic diversity (θ) calculated for each LEE gene using a Watterson estimate is represented as a spot below the relevant gene.