Quantification of LIP-mediated cell engulfment.

<p>A, Panel a shows the percent of Ad-LIP MDA-MB-468 cells that are double positive for GFP and CellTracker label. Panel b shows the percent of control Ad-GFP MDA-MB-468 cells that are double positive for GFP and CellTracker label. B, Quantification of the percent of GFP positive cells that have engulfed uninfected CellTracker labeled cells. Results are shown for 16 different experiments with a p-value of <0.0001 using paired t-test and Wilcoxon matched pairs test for statistical analysis. C, Quantification of the percent of GFP positive cells that have engulfed uninfected CellTracker labeled cells after treatment with 40 µM of the ROCK inhibitor, Y-27632. Results are shown for 5 different experiments with a p-value of <0.0001 using ANOVA followed by the Student-Newman-Keuls multiple comparisons test.