<p>The anti-nociceptive effect was measured 30 min after morphine injection. The baseline PWLs were determined before chronic morphine exposure (10 µg i.t., twice daily for 6 days). On day 7, rats were injected intrathecally with LV-NC or LV-shPKCã. Data are presented as mean ± SD. *<i>P</i><0.05, compared with the corresponding value in the saline control group.</p
<p>(A) Normalized changes in paw withdrawal latency are shown in response to a heat stimulus (averag...
Opioids are consistently prescribed as pain management drugs for patients. However, the physiologica...
<p><b>A</b>, <b>C</b>) The development of thermal hyperalgesia (A) and mechanical allodynia (C) was ...
<p>(A) Flow chart of the experimental protocol. (B) Rats were administered twice daily injections of...
<p>Separate groups of naïve rats received intraplantar bradykinin (25 μg) 15 minutes before co-injec...
<p><b>(A)</b> Timeline of treatments used in these experiments. <b>(B)</b> Mechanical ipsilateral pa...
Opioid withdrawal syndrome is a critical component of opioid abuse and consists of a wide array of s...
International audienceIn thermoneutral conditions, rats display cyclic variations of the vasomotion ...
<p><b>A)</b> Following baseline thermal testing (Pre), separate groups of rats received intraplantar...
<p>(A) The time course of CFA-induced thermal hyperalgesia. A significant decrease was observed in P...
<p>Paw withdrawal latencies to thermal stimuli and withdrawal thresholds to von Frey hairs in wt and...
<p>Mechanical antiallodynic (A), thermal antihyperalgesic (B) and thermal antiallodynic (C) effects ...
The present study investigated the alteration in intracerebroventricular administration of substance...
<p>Mechanical threshold and tail flick latency were evaluated daily before injection (D<sub>-4</sub>...
Rationale: The largest amount of researches on the hot-plate test was carried out using quantitative...
<p>(A) Normalized changes in paw withdrawal latency are shown in response to a heat stimulus (averag...
Opioids are consistently prescribed as pain management drugs for patients. However, the physiologica...
<p><b>A</b>, <b>C</b>) The development of thermal hyperalgesia (A) and mechanical allodynia (C) was ...
<p>(A) Flow chart of the experimental protocol. (B) Rats were administered twice daily injections of...
<p>Separate groups of naïve rats received intraplantar bradykinin (25 μg) 15 minutes before co-injec...
<p><b>(A)</b> Timeline of treatments used in these experiments. <b>(B)</b> Mechanical ipsilateral pa...
Opioid withdrawal syndrome is a critical component of opioid abuse and consists of a wide array of s...
International audienceIn thermoneutral conditions, rats display cyclic variations of the vasomotion ...
<p><b>A)</b> Following baseline thermal testing (Pre), separate groups of rats received intraplantar...
<p>(A) The time course of CFA-induced thermal hyperalgesia. A significant decrease was observed in P...
<p>Paw withdrawal latencies to thermal stimuli and withdrawal thresholds to von Frey hairs in wt and...
<p>Mechanical antiallodynic (A), thermal antihyperalgesic (B) and thermal antiallodynic (C) effects ...
The present study investigated the alteration in intracerebroventricular administration of substance...
<p>Mechanical threshold and tail flick latency were evaluated daily before injection (D<sub>-4</sub>...
Rationale: The largest amount of researches on the hot-plate test was carried out using quantitative...
<p>(A) Normalized changes in paw withdrawal latency are shown in response to a heat stimulus (averag...
Opioids are consistently prescribed as pain management drugs for patients. However, the physiologica...
<p><b>A</b>, <b>C</b>) The development of thermal hyperalgesia (A) and mechanical allodynia (C) was ...