<p>Plots illustrate the power of the methods when the total number of associated SNPs equals 100 (plot (A)) and 200 (plot(B)), the effect sizes are and for both plots.</p
<p>As indicated, the total amount of variance explained, rather than the number of SNPs the effect i...
This study explored a semi-parametric method built upon reproducing kernels for estimating and testi...
<p>The x-axis represents the estimated effect sizes in mean differences. The horizontal lines show t...
<p>Plots illustrate the power of the methods when the total number of associated SNPs equals 100, th...
<p>Power of the methods for a pathway of size 20. 50 genes in total have effects. The effect size o...
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>The plot shows the powers (y-axis) of each method over the different LD and MAF structures (x-axi...
<p>The plot shows the powers (y-axis) of each method over the different LD and MAF structures (x-axi...
<p>The mean power of the methods is computed for all the scenarios for the three different tested pa...
<p>Footnote: Note that in some scenarios, different methods overlap. This is the case for scenario 1...
<p>Note: The horizontal axis denotes the positions of the causal SNPs in the corresponding genes (Ai...
<p>Note: In <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062129#pone-00621...
<p>The dashed line represent the median power, with the covered area is the inter quantile range of ...
<p>Power to identify SNP1, SNP2, as significant for additive (A) and co-dominant (B) correction.</p
<p>The plot shows the effect size of each tested parameter threshold combination utilizing Cohens' d...
<p>As indicated, the total amount of variance explained, rather than the number of SNPs the effect i...
This study explored a semi-parametric method built upon reproducing kernels for estimating and testi...
<p>The x-axis represents the estimated effect sizes in mean differences. The horizontal lines show t...
<p>Plots illustrate the power of the methods when the total number of associated SNPs equals 100, th...
<p>Power of the methods for a pathway of size 20. 50 genes in total have effects. The effect size o...
<p>(A) 100% causal SNVs within all genes, estimated with SKAT. (B) 100% causal SNVs within each gene...
<p>The plot shows the powers (y-axis) of each method over the different LD and MAF structures (x-axi...
<p>The plot shows the powers (y-axis) of each method over the different LD and MAF structures (x-axi...
<p>The mean power of the methods is computed for all the scenarios for the three different tested pa...
<p>Footnote: Note that in some scenarios, different methods overlap. This is the case for scenario 1...
<p>Note: The horizontal axis denotes the positions of the causal SNPs in the corresponding genes (Ai...
<p>Note: In <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0062129#pone-00621...
<p>The dashed line represent the median power, with the covered area is the inter quantile range of ...
<p>Power to identify SNP1, SNP2, as significant for additive (A) and co-dominant (B) correction.</p
<p>The plot shows the effect size of each tested parameter threshold combination utilizing Cohens' d...
<p>As indicated, the total amount of variance explained, rather than the number of SNPs the effect i...
This study explored a semi-parametric method built upon reproducing kernels for estimating and testi...
<p>The x-axis represents the estimated effect sizes in mean differences. The horizontal lines show t...
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