Analysis of larval phenotype and motility for the Dundee 10,041 Compound Library.

<p>(<b>A</b>) Combined phenotype and motility analysis of wells treated with 10 µM of the compounds. Visually assessed hits are shown in red, non-hits in blue and non-hits with compound crystals in the well in yellow. The hit region for automated image analysis as determined above using the anti-schistosome compounds is delineated by the dashed lines. (<b>B</b>) Performance of the Automated image analysis categorization compared to the visual assessments. (<b>C</b>) Z factor analysis of phenotype (open) and motility (closed) per plate of the Dundee compound library.