Effects of CORM-3 on metabolic parameters.

<p>(A) Oral glucose tolerance and (B) insulin tolerance tests were performed on ND (black circles), ND + CORM-3 (black triangles), HFD (black squares) and HFD + CORM-3 (white diamonds) mice. Data are means ± SEM. n = 10 in each group. (a) p<0.05 between HFD and ND; (b) p<0.05 between HFD + CORM-3 and ND. (C) Plasma cholesterol and (D) true triglyceride measurements were performed on 6–10 different samples in each group. Data are means ± SEM. (E) Basal oxygen uptake (<i>V</i>O₂) and carbon dioxide rejection (<i>V</i>CO₂), (F) respiratory exchange ratio (RER). Data represent means ± SEM. n = 5–7 in each group, * p<0.05 vs. ND. White bars = ND; vertically hatched bars = ND + CORM-3; black bars = HFD; crosshatched bars = HFD + CORM-3.