<p>Gray dots: response below the cut-off to any of the 6 peptide pools; red dots: response above the cut-off to any of the 6 peptide pools. For the vaccine groups, the overlaid box plot summarizes the positive responses (i.e., the median, 1<sup>st</sup> and 3<sup>rd</sup> quartiles and minimum/maximum). For the baseline (BL) and placebo (Pbo) group, the box plot summarizes the negative responses and the red dot displays the single positive response at baseline.</p
<p>At 2 weeks post final immunization in each of groups 1–5, PBMCs were collected and tested for GRI...
<p><sup>a</sup>Frequency of responders given as percentage of total number of evaluable vaccinees.</...
Frequency of vaccine-specific CD4+ T cells measured at different time points. The mean value of the ...
<p>The y-axis shows the SFC/10<sup>6</sup> PBMC on a half-log scale and the x-axis shows the time po...
<p>Responses at baseline (BL), 2 weeks after <i>prime (Prm)</i> and 2 weeks after boost (Bst) are sh...
<p>IFN-γ ELISpot to (A) Gag and (B) the Env peptide pool after the second HIV-MVA, at the time of fi...
<p>The panels show individual background-subtracted IFN-γ ELISPOT counts to each antigen at 2 weeks ...
(A) the DNA vaccine-specific Gag Smi peptide pool and, (B) the HIV-MVA vaccine-specific Gag CMDR, (C...
<p>Magnitude of HIV-1-specific T cell responses measured by IFN-γ-based ELISPOT is shown. A) Total r...
<p>(A) To evaluate T cell response breadth, PBMC from different patient groups were stimulated with ...
<p>CD4+ and CD8+ background-adjusted T-cell responses as determined by intracellular cytokine staini...
<p>Graphs represent means SFU/10<sup>6</sup> cells + standard deviations of the responses to A) Gag ...
<p>HIV-specific IFN-γ ELISpot responses two weeks after the first (upper panels) and second (lower p...
Frequency of vaccine-specific CD8+ T cells at different time points. The mean value of the total res...
<p>Average magnitude of IFN-γ ELISPOT responses in SFC/10<sup>6</sup> cells (Y-axis) at each time po...
<p>At 2 weeks post final immunization in each of groups 1–5, PBMCs were collected and tested for GRI...
<p><sup>a</sup>Frequency of responders given as percentage of total number of evaluable vaccinees.</...
Frequency of vaccine-specific CD4+ T cells measured at different time points. The mean value of the ...
<p>The y-axis shows the SFC/10<sup>6</sup> PBMC on a half-log scale and the x-axis shows the time po...
<p>Responses at baseline (BL), 2 weeks after <i>prime (Prm)</i> and 2 weeks after boost (Bst) are sh...
<p>IFN-γ ELISpot to (A) Gag and (B) the Env peptide pool after the second HIV-MVA, at the time of fi...
<p>The panels show individual background-subtracted IFN-γ ELISPOT counts to each antigen at 2 weeks ...
(A) the DNA vaccine-specific Gag Smi peptide pool and, (B) the HIV-MVA vaccine-specific Gag CMDR, (C...
<p>Magnitude of HIV-1-specific T cell responses measured by IFN-γ-based ELISPOT is shown. A) Total r...
<p>(A) To evaluate T cell response breadth, PBMC from different patient groups were stimulated with ...
<p>CD4+ and CD8+ background-adjusted T-cell responses as determined by intracellular cytokine staini...
<p>Graphs represent means SFU/10<sup>6</sup> cells + standard deviations of the responses to A) Gag ...
<p>HIV-specific IFN-γ ELISpot responses two weeks after the first (upper panels) and second (lower p...
Frequency of vaccine-specific CD8+ T cells at different time points. The mean value of the total res...
<p>Average magnitude of IFN-γ ELISPOT responses in SFC/10<sup>6</sup> cells (Y-axis) at each time po...
<p>At 2 weeks post final immunization in each of groups 1–5, PBMCs were collected and tested for GRI...
<p><sup>a</sup>Frequency of responders given as percentage of total number of evaluable vaccinees.</...
Frequency of vaccine-specific CD4+ T cells measured at different time points. The mean value of the ...