Reconstitution of iNKT cells promotes tumor growth in Jalpha18^−/− mice.

<p>(A) Liver mononuclear cells from WT (iNKT) and Jalpha18^−/− mice (Control) were adoptively transferred into Jalpha18^−/− recipients. 10⁵ lymphoma cells were transplanted one day later and tumor growth in the liver was analyzed on day 10 post-transplant. Representative flow plots are gated on CD11b^-Gr1^-CD4^-CD8^- cells, and the number on the plot represents the percentage of gated cells that were CD19⁺GFP⁺ tumor cells. (B-C) The frequency (B) of tumor cells among all IHL and the absolute number of tumor cells (C) from a total of 6–7 mice in three independent experiments are shown. *p<.05.