<p>System 1 is the model based on the proteomic data only with normalized protein concentrations. System 2 is the model based on both proteomic and other experimental data with absolute protein concentrations. Except the variables in this table, the initial conditions of other variables are zeros. The concentrations of three phosphatases were calculated based on both the absolute kinase concentration in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042230#pone.0042230-Fujioka1" target="_blank">[30]</a> and ratio of phosphatase concentration to the corresponding kinase concentration in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042230#pone.0042230-Schoeberl1" target="_blank">[26]</a>.</p
<p>The points are computed from all proteins at all synthesis rates for which the concentration in t...
<p>The value of Property 3 (<i>p3: = MOMP release alive</i>) is represented as a function of the XIA...
<p>The graphs are obtained by solving Eqs.(16)-(18) with the following parameters : , M, M; On the l...
<div><p>The advances in proteomics technologies offer an unprecedented opportunity and valuable reso...
The advances in proteomics technologies offer an unprecedented opportunity and valuable resources to...
<p>Investigation of the dependence of STAT3 phosphorylation on the relative activities of JAK and SH...
A: State classification indices for Phosphatase1; B: comparison of the output ERK-PP and Phosphatase...
<p>Different conditions correspond to different treatments (see right panel of <a href="http://www.p...
<p>(<b>A</b>) The distribution of kinase saturation levels, (the ratio of kinase concentration to s...
<p><b>A</b> Schematic representation of a five-step kinase cascade (S…extracellular stimulus; and …...
<p>Left: Values of Property 2 evaluated on cell simulated behaviors and represented as a function of...
<p>A: The MF approximation formula is used to relate the fraction of phosphorylated protein with th...
<p>Shading represents the percentage of expressed proteins within each metabolic category. Assignmen...
<p>(A) Average saturation of enzymes in all of the evolved ultrasensitive networks. The average satu...
<p>(<b>A</b>) Network diagram for the canonical pathway, which is the null hypothesis (H0). The phos...
<p>The points are computed from all proteins at all synthesis rates for which the concentration in t...
<p>The value of Property 3 (<i>p3: = MOMP release alive</i>) is represented as a function of the XIA...
<p>The graphs are obtained by solving Eqs.(16)-(18) with the following parameters : , M, M; On the l...
<div><p>The advances in proteomics technologies offer an unprecedented opportunity and valuable reso...
The advances in proteomics technologies offer an unprecedented opportunity and valuable resources to...
<p>Investigation of the dependence of STAT3 phosphorylation on the relative activities of JAK and SH...
A: State classification indices for Phosphatase1; B: comparison of the output ERK-PP and Phosphatase...
<p>Different conditions correspond to different treatments (see right panel of <a href="http://www.p...
<p>(<b>A</b>) The distribution of kinase saturation levels, (the ratio of kinase concentration to s...
<p><b>A</b> Schematic representation of a five-step kinase cascade (S…extracellular stimulus; and …...
<p>Left: Values of Property 2 evaluated on cell simulated behaviors and represented as a function of...
<p>A: The MF approximation formula is used to relate the fraction of phosphorylated protein with th...
<p>Shading represents the percentage of expressed proteins within each metabolic category. Assignmen...
<p>(A) Average saturation of enzymes in all of the evolved ultrasensitive networks. The average satu...
<p>(<b>A</b>) Network diagram for the canonical pathway, which is the null hypothesis (H0). The phos...
<p>The points are computed from all proteins at all synthesis rates for which the concentration in t...
<p>The value of Property 3 (<i>p3: = MOMP release alive</i>) is represented as a function of the XIA...
<p>The graphs are obtained by solving Eqs.(16)-(18) with the following parameters : , M, M; On the l...