Relative abundance of bacterial taxa in saliva samples at the class level.

<p>The sample order corresponds to the increase in <i>Candida</i> load in the samples (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042770#pone.0042770.s006" target="_blank">Table S2</a>). The <i>Candida</i> load was measured as proportion of ITS gene over 16S gene abundance by qPCR. Increase in <i>Candida</i> load correlated positively with reads classified as Bacilli (<i>p</i> = 0.013; Spearman’s rho 0.274), while class Bacteroidia (<i>p</i> = 0.001; Spearman’s rho −0.360), Flavobacteria (<i>p</i> = 0.003; Spearman’s rho −0.322), Fusobacteria (<i>p</i> = 0.012; Spearman’s rho −0.275) correlated negatively with the <i>Candida</i> load (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042770#pone.0042770.s001" target="_blank">Figure S1</a>).