Serial µCT imaging during bleomycin-induced lung fibrosis.

<p>(A) 3D micro-CT imaging of progressive pulmonary fibrosis in a representative bleomycin-treated mouse over time. (B) Mean EEV over time after induction of fibrosis. (data are mean +/− SEM, differences were significant over time (p = 0.0061) and per group (p = 0.0291) when comparing treated vs non-treated mice exposed to bleomycin (n = 4 vs 5). Adding the non-bleomycin treated control group (n = 7) also showed significant interaction between time and treatment group (p = 0.007).