Que protectes the spinal cord from demyelination and loss of oligodendrocytes.

<p><b>A.</b> MBP immunofluorescent staining displays an obvious decrease of myelin (arrows) in the white matter of the spinal cord in the untreated EAE controls (N = 5). Post-treatment with Que (N = 5) protects myelin from breakdown and displays a similar fluorescence intensity to the unimmunized controls (N = 5). <b>B.</b> Luxol Fast Blue (LFB) staining indicates a similar pattern after Que treatment (arrows). <b>C.</b> Que prevents the loss of CC1⁺ oligodendrocytes as compared with the untreated controls. Quantification of the observations is provided in the bar graphs. (*, <i>p<</i>0.05). Scale bar A = B = 0.5 mm, C = 0.2mm.