<p>(<b>a</b>) and (<b>b</b>) show the hydrogen-bonding interactions provided by two WD<sub>b–a</sub> of neighboring WD40 blades in 3D and 2D, respectively. Those residues composed of WD<sub>b–a</sub> bulges are shown in stick as numbered in BUB3 (1YFQ). The hydrogen bonds, HB<sub>1</sub> and HB<sub>2</sub>, are formed inter-blade by Ser213 backbone (X+1 position) and Ser212 (X position) side chain with Val254 (R<sub>1</sub>-1) at the other WD40 blade. (<b>c</b>) χ2 dihedral angles of R<sub>1</sub> residues. As χ2 is at gauche-conformation, Arg points upward. If χ2 is at anti-conformation, Arg point to WD40-1, which is unacceptable due to the crowdedness.</p
<p>In each case, the structure alignment was done locally to emphasize the local effects. (A) The su...
<div><p>(a) A stereo view of the composite β-sheet: One of the β-sheets of the V<sub>H</sub> consis...
<p>The hydrogen bond interactions between contiguous amino acid residues based on a 3.2 Å cut-off ha...
<p>Although the enclosed WD40 blade has the different order in sequence, their hydrogen bonds, β-bul...
<p><b>(A)</b> WD40 domain in 2D scheme. The definitions of WD40 blades and WD40 repeats are differen...
<p>The side chain of W236 forms a hydrogen bond with E358. The backbone of GLA is shown as a ribbon ...
<p>A sidechain contact is defined if the center of mass of sidechains between two residues is less t...
The hydrogen bond (H-bond) cooperativity in the β-sheet of GB3 is investigated by a NMR hydrogen/deu...
<p>Loop 1 (residues 73–90), loop2 (residues 200–211), β-sheet 1 (residues 91–112), and the linker (r...
<p>Hydrogen-bond interactions among the residues belonging to the diverging β-turn and those of the ...
The geometry of interactions of planar residues is nonrandom in protein tertiary structures and give...
<p>Panels A and C correspond to the WT HsTIM, whereas B and D correspond to the mutant N15D. (A) Hyd...
<div><p>The analysis of 36 available crystal structures of WD40 repeat proteins reveals widespread e...
International audienceβ-Sheets are quite frequent in protein structures and are stabilized by regula...
<p>Electrostatic interaction node maps generated from the results of the multi conformer continuum e...
<p>In each case, the structure alignment was done locally to emphasize the local effects. (A) The su...
<div><p>(a) A stereo view of the composite β-sheet: One of the β-sheets of the V<sub>H</sub> consis...
<p>The hydrogen bond interactions between contiguous amino acid residues based on a 3.2 Å cut-off ha...
<p>Although the enclosed WD40 blade has the different order in sequence, their hydrogen bonds, β-bul...
<p><b>(A)</b> WD40 domain in 2D scheme. The definitions of WD40 blades and WD40 repeats are differen...
<p>The side chain of W236 forms a hydrogen bond with E358. The backbone of GLA is shown as a ribbon ...
<p>A sidechain contact is defined if the center of mass of sidechains between two residues is less t...
The hydrogen bond (H-bond) cooperativity in the β-sheet of GB3 is investigated by a NMR hydrogen/deu...
<p>Loop 1 (residues 73–90), loop2 (residues 200–211), β-sheet 1 (residues 91–112), and the linker (r...
<p>Hydrogen-bond interactions among the residues belonging to the diverging β-turn and those of the ...
The geometry of interactions of planar residues is nonrandom in protein tertiary structures and give...
<p>Panels A and C correspond to the WT HsTIM, whereas B and D correspond to the mutant N15D. (A) Hyd...
<div><p>The analysis of 36 available crystal structures of WD40 repeat proteins reveals widespread e...
International audienceβ-Sheets are quite frequent in protein structures and are stabilized by regula...
<p>Electrostatic interaction node maps generated from the results of the multi conformer continuum e...
<p>In each case, the structure alignment was done locally to emphasize the local effects. (A) The su...
<div><p>(a) A stereo view of the composite β-sheet: One of the β-sheets of the V<sub>H</sub> consis...
<p>The hydrogen bond interactions between contiguous amino acid residues based on a 3.2 Å cut-off ha...