Survival of optic nerve axons in KO rats, compared to WT rats following IOP elevation.
- Alena Z. Minton (143795)
- Nitasha R. Phatak (143797)
- Dorota L. Stankowska (143799)
- Shaoqing He (143800)
- Hai-Ying Ma (143802)
- Brett H. Mueller (143803)
- Ming Jiang (11433)
- Robert Luedtke (143806)
- Shaohua Yang (143807)
- Colby Brownlee (143809)
- Raghu R. Krishnamoorthy (143812)
Publication date
August 2012
DOIAbstract
<p>IOP was elevated in one eye of WT and KO rats, while the other eye served as corresponding contralateral control. The rats were maintained for 4 weeks following IOP elevation. Rats were sacrificed and optic nerve sections were stained with paraphenylenediamine. Dark spots (white arrows) indicate dying/degenerating axons. Glial scar formation (black arrow heads) was more abundant in WT rats, compared to KO rats in IOP elevated eyes. Scale bar indicates 20 µm.</p
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