SLX-1 and HIM-18 are required for both mitotic and meiotic DNA repair.

<p>(A) Mean number of RAD-51 foci per nucleus. Histograms depict the quantitation of RAD-51foci in germlines of the indicated genotypes. Quantitative analysis of RAD-51 foci depicted in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002888#pgen.1002888.s003" target="_blank">Figure S3</a>, is represented here as the mean number of RAD-51 foci observed per nucleus (y-axis) on each zone along the germline axis (x-axis) for all indicated genotypes. Error bars represent standard error of the mean. To manifest the levels of meiotic RAD-51 foci, mean number of RAD-51 foci in <i>slx-1;spo-11</i> double mutants at each zone was subtracted from <i>slx-1</i> mutants ((<i>slx-1</i>) - (<i>slx-1;spo-11</i>)). Colored asterisks indicate statistical significance between different genotypes (wild type, <i>slx-1, him-18 and slx-1;him-18</i>). (B) Quantitation of germline apoptosis. Apoptotic corpses stained by acridine orange were scored. N = number of gonad arms scored for each genotype. Colored asterisks indicate statistical significance between different genotypes.