Human T-cells in Hu-PBMC NSG mice display skin homing capabilities.

<p>Peripheral blood, spleen and bone marrow were harvested from irradiated Hu-PBMC NSG mice at the indicated time points. Representative gating of peripheral blood is shown in (A). CD3⁺ T-cells were analysed for (B) CLA expression and (C) CD4 to CD8 ratio of CLA expressing CD3⁺ T-cells. <b>Black bars represent human PBMC phenotype pre-injection.</b> Unpaired t test was performed. Each data point represents the mean ±SEM and are compiled from 2 independent experiments (<i>n</i> = 7).