Reduced neural progenitor populations in the SVZ of TLX−/− brains.

<p><b>A.</b> short-term (6 hr pulse) BrdU labeling along with Mash1 and TLX staining in the SVZ of wild type (WT) and TLX−/− brains. The top panels show Mash1 single staining and the bottom panels show merged images of Mash1, brdU and TLX triple staining. B. Quantification of Mash1+ cells in the SVZ of WT and TLX−/− brains. Data are represented as means ± s.d. *p<0.001 by Student's t-test. C. Quantification of Mash1+Ki67+ cells from Mash1+ cells in the SVZ of WT and TLX−/− brains. Data are represented as means ± s.d. *p<0.001 by Student's t-test. <b>D.</b> DCX and TLX staining in the SVZ of WT and TLX−/− brains. The top panels show DCX single staining and the bottom panels show merged images of DCX and TLX double staining. Scale bar, 20 µm for all panels.