Effect of the presence of PTX and caged PTXs on the microtubule cytoskeleton of living cells.

<p>Fluorescence microscopy images of HeLa cells stably expressing GFP-tubulin imaged after 1 h (<b>A</b>) and 24 h (<b>B</b>) incubation in medium containing DMSO, PTX and caged derivatives at the indicated concentrations. White arrows indicate the cell edge deprived of microtubules. Scale bars: 20 µm. See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043657#pone.0043657.s009" target="_blank">Fig. S5</a> for images of assays with pre-irradiated compounds.