Mapping sRNAs to human mitochondrial genome.

<p>The sequences obtained from the mitochondrial sRNA libraries from HEK293 and HeLa were aligned to mitochondrial genome. (A) An overview of mitochondria-associated sRNAs from HEK293 that aligned to mitochondrial genome. (B) An overview of mitochondria-associated sRNAs from HeLa that aligned to mitochondrial genome. (C) The miRNAs and putative novel miRNAs that aligned to mtDNA (determined by SOAP, MapMi, BLASTN and RNAhybrid) were mapped on mtDNA using Dynamo Software tool. The locations of known miRNAs and putative novel miRNAs that aligned to mtDNA are marked in red and blue respectively. If more than 1 miRNA aligned to same position, only 1 miRNA was marked.