<p>Thrombin generation profiles were generated from each individual’s plasma composition (n = 364), containing fII, fV, fVII, fVIII, fIX, fX, AT, TFPI and PC and a 5 pM Tf initiator. The mean thrombin curve is shown in maroon with the standard deviation in salmon. A control curve, representing mean physiologic concentrations of each factor is illustrated in gold as a comparison.</p
Accessible online at: www.karger.com/pht Key Words Thrombin generation W Mucocutaneous haemorrhages ...
<p>Plasma factor composition was used to generate time courses of thrombin generation, thrombin para...
The outcome of congenital fibrinogen defects (CFD) is often unpredictable. Standard coagulation assa...
<p>Individuals within the family were segregated by <b>A)</b> Protein C mutation, <b>B)</b> Prothomb...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...
<p>Individuals were selected with disparate factor composition, but similar thrombin generation prof...
<p>Individuals within the family were segregated by gender for <b>A)</b> Protein C mutation, <b>B)</...
<div><p>The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appea...
<p>Plasma factor composition for 32 individuals was used to generate time courses of thrombin genera...
<p>FVIII-depleted plasma was reconstituted with FVIII variants and thrombin generation was measured ...
In vitro thrombin generation, which reflects an individual's plasma coagulation potential and has be...
SummaryWe investigated the relation between clotting factor concentration, the parameters of the thr...
<p>Each individual in the population (6,561) is defined by 4 thrombin parameters and their phenotype...
The clinical phenotype of patients with haemophilia A (HA) often differs between individuals with th...
We investigated the relation between clotting factor concentration, the parameters of the thrombin g...
Accessible online at: www.karger.com/pht Key Words Thrombin generation W Mucocutaneous haemorrhages ...
<p>Plasma factor composition was used to generate time courses of thrombin generation, thrombin para...
The outcome of congenital fibrinogen defects (CFD) is often unpredictable. Standard coagulation assa...
<p>Individuals within the family were segregated by <b>A)</b> Protein C mutation, <b>B)</b> Prothomb...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...
<p>Individuals were selected with disparate factor composition, but similar thrombin generation prof...
<p>Individuals within the family were segregated by gender for <b>A)</b> Protein C mutation, <b>B)</...
<div><p>The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appea...
<p>Plasma factor composition for 32 individuals was used to generate time courses of thrombin genera...
<p>FVIII-depleted plasma was reconstituted with FVIII variants and thrombin generation was measured ...
In vitro thrombin generation, which reflects an individual's plasma coagulation potential and has be...
SummaryWe investigated the relation between clotting factor concentration, the parameters of the thr...
<p>Each individual in the population (6,561) is defined by 4 thrombin parameters and their phenotype...
The clinical phenotype of patients with haemophilia A (HA) often differs between individuals with th...
We investigated the relation between clotting factor concentration, the parameters of the thrombin g...
Accessible online at: www.karger.com/pht Key Words Thrombin generation W Mucocutaneous haemorrhages ...
<p>Plasma factor composition was used to generate time courses of thrombin generation, thrombin para...
The outcome of congenital fibrinogen defects (CFD) is often unpredictable. Standard coagulation assa...