<p>Individuals within the family were segregated by gender for <b>A)</b> Protein C mutation, <b>B)</b> Prothrombin mutation, and <b>C)</b> Thrombosis history. The groups with the mutation/history are shown in green (+SD) and without the mutation/history are shown in grey (–SD) A control curve, representing mean physiologic concentrations of each factor is illustrated in gold as a comparison.</p
In vitro thrombin generation, which reflects an individual's plasma coagulation potential and has be...
The aim of this thesis is to evaluate thrombin generation in patients with thrombophilia (Paper I), ...
<div><p>In terms of its soluble precursors, the coagulation proteome varies quantitatively among app...
<p>Individuals within the family were segregated by <b>A)</b> Protein C mutation, <b>B)</b> Prothomb...
<p>Males to females with an additional category of risk were compared for either PC mutation (panels...
<p>Individuals were selected with disparate factor composition, but similar thrombin generation prof...
<p>Thrombin generation profiles were generated from each individual’s plasma composition (n = 364), ...
<div><p>The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appea...
<p>Plasma factor composition for 32 individuals was used to generate time courses of thrombin genera...
<p>Each individual in the population (6,561) is defined by 4 thrombin parameters and their phenotype...
SummaryWe used two-locus segregation analysis to test whether an unknown genetic defect interacts wi...
<p>Plasma factor composition was used to generate time courses of thrombin generation, thrombin para...
Protein S deficiency is a known risk factor for thrombosis. The coexistence of phenotypic type I (re...
Detection of a Protein C Gene Mutation Present in the Asymptomatic and not in the Thrombosis-Prone L...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...
In vitro thrombin generation, which reflects an individual's plasma coagulation potential and has be...
The aim of this thesis is to evaluate thrombin generation in patients with thrombophilia (Paper I), ...
<div><p>In terms of its soluble precursors, the coagulation proteome varies quantitatively among app...
<p>Individuals within the family were segregated by <b>A)</b> Protein C mutation, <b>B)</b> Prothomb...
<p>Males to females with an additional category of risk were compared for either PC mutation (panels...
<p>Individuals were selected with disparate factor composition, but similar thrombin generation prof...
<p>Thrombin generation profiles were generated from each individual’s plasma composition (n = 364), ...
<div><p>The underlying cause of thrombosis in a large protein C (PC) deficient Vermont kindred appea...
<p>Plasma factor composition for 32 individuals was used to generate time courses of thrombin genera...
<p>Each individual in the population (6,561) is defined by 4 thrombin parameters and their phenotype...
SummaryWe used two-locus segregation analysis to test whether an unknown genetic defect interacts wi...
<p>Plasma factor composition was used to generate time courses of thrombin generation, thrombin para...
Protein S deficiency is a known risk factor for thrombosis. The coexistence of phenotypic type I (re...
Detection of a Protein C Gene Mutation Present in the Asymptomatic and not in the Thrombosis-Prone L...
<p>FVIII concentration for each variant was adjusted to 5 ng/ml in complete medium. Subsequently eac...
In vitro thrombin generation, which reflects an individual's plasma coagulation potential and has be...
The aim of this thesis is to evaluate thrombin generation in patients with thrombophilia (Paper I), ...
<div><p>In terms of its soluble precursors, the coagulation proteome varies quantitatively among app...