Surface expression of co-stimulatory molecules by DCs in response to <i>S. suis</i>.

<p>WT, MyD88^−/−, and TLR2^−/− DCs (10⁶ cells/ml) were stimulated with S. <i>suis</i> (10⁶ CFU/ml) for 16 h. Non-stimulated cells served as negative control (C−). (A) Percentage of CD40 positive cells. (B) Percentage of CD86^high positive cells. (C) Percentage of MHC-II^high positive cells. Twenty thousand gated events were acquired per sample. Quadrants were drawn based on FITC- and PE-control stains and were plotted on logarithmic scales. CD40, CD86 and MHC-II histograms were obtained by gating cells based on positive CD11c staining. * P<0.05 denotes values that are significantly lower than those obtained with WT DCs.