Immunohistochemical analysis.

<p>A-C. Staining patterns of HLA-I, ß2-m and ERAP1, respectively. (Other APM components TAP1, TAP2, LMP2, LMP7, calnexin, calreticulin, ERp57, and tapasin staining shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044952#pone.0044952.s001" target="_blank">Figure S1</a>), Panels A1–C1 depict normal uterine cervix tissue with normal protein expression. Panels A2-C2 show cervical intraepithelial neoplasia with partial loss of protein expression. Panels A3-C3 show cervical carcinoma with weak or total loss of protein expression.