Genome-wide mRNA levels.

<p>mRNA was extracted from cell collected from the chemostat experiments at different time points and measured by DNA arrays (see <i>Methods</i>). Two major clusters were found using a self-organized maps clustering method, with induced (red) and repressed (green) genes with 2-fold or more compared to the initial steady-state expression levels for: (a) pNdd1-<i>HIS3</i> strain with 1051 genes induced and 835 repressed; (b) a “twin” chemostat to that presented in (a) with 526 genes induced and 618 repressed; (c) pSwi4-<i>HIS3</i> strain with 616 genes induced and 562 repressed; (d) another chemostat with the pSwi4-<i>HIS3</i> strain with 464 genes induced and 476 repressed. The expression levels are presented in log2 values. The error bars represent the standard deviation of expression values among genes belonging to each cluster. The population growth dynamics as measured by the cell density in the chemostats is depicted by the gray curves.