MiR-370-induced prostate cancer cell proliferation is mediated by FOXO1. A,

<p>Real-time PCR analysis of <i>p21^Cip1, p27^Kip1</i> and cyclin D1 mRNA expression in the indicated cells. <i>GAPDH</i> was used as a loading control 48 hours after transfection. <b>B,</b> Luciferase activity assay of the indicated cells transfected with a FOXO1 reporter 48 hours after transfection. <b>C,</b> MTT assay of prostate cancer cells transfected with miR-370 mimic, co-transfected with miR-370 and FOXO1, or co-transfected with miR-370 and FOXO1-3′-UTR.