Infectivity to mosquitoes is governed by gametocyte density and other factors.

<p>The probability of mosquito infection versus gametocyte count for A) varying survival factors; B) varying effect of inflammatory immune response on gametocyte success. Inflammatory cytokine mediated gametocyte inactivation can explain widely varying mosquito infection rates even for a single individual; and C) data for the probability of mosquito infection with a model example survival factor of 100 and a cytokine effect of 0.94.