GenoCNA analysis comparing HGSC cases based on p53 immunoreactivity.

<p>GenoCNA analysis comparing the mean copy number, on a per SNP basis, of the 44 samples expressing p53 mutant protein to that of the 24 p53 protein null HGSC cases for chromosomes 1 (A), 8 (B) and 12 (C), which contain regions significantly gained in the HGSC cases expressing p53 mutant protein as compared to the p53 protein null HGSC cases (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0045484#pone-0045484-g003" target="_blank">Figure 3B, C</a>). Points on the plot represent –log10 of p-values from t-tests comparing the means in the two groups. Blue bars indicate regions of significant gain.