MiRNAs that regulate insulin-stimulated adipogenesis.

<p>A reverse search for miRNAs regulating mRNAs important in preadipocyte differentiation, lipogenesis and antilipolysis was performed. The relations between miRNAs and mRNAs were illustrated. <i>INSR</i>: insulin receptor; IRS1/2: insulin receptor substrate 1/2; <i>PI3K</i>: phosphoinositide-3-kinase, catalytic, polypeptide; <i>PIP3</i>: interaction protein for cytohesin exchange factors 1; <i>PDK1/2</i>: pyruvate dehydrogenase kinase, isozyme 1/2; <i>S6k1</i>: ribosomal protein S6 kinase, polypeptide 1; <i>aPKC</i>: protein kinase C, alpha; <i>SREBP1</i>: sterol regulatory element binding transcription factor 1; <i>AKT</i>: v-akt murine thymoma viral oncogene homolog; <i>TSC2</i>: tuberous sclerosis 2; <i>Rheb</i>: Ras homolog enriched in brain; <i>NEcdin</i>: necdin homolog (mouse); <i>CREB</i>: cAMP responsive element binding protein, <i>FOXO1</i>: RNA binding protein, fox-1 homolog 1; <i>FOXOA2</i>: forkhead box A2; <i>GATA2/3</i>: GATA binding protein 2/3; <i>PPARγ</i>: peroxisome proliferator-activated receptor gamma; <i>C/EBPα/β/γ/δ/ζ</i>: CCAAT/enhancer binding protein alpha/beta/gamma/delta/zeta; <i>KROX20</i>: early growth response 2, <i>KLF2/5</i>: Kruppel-like factor 2/5 (lung); <i>wnt10b</i>: wingless-type MMTV integration site family, member 10b; <i>β-catenin</i>: (cadherin-associated protein), beta 1; <i>Glut4</i>: solute carrier family 2 (facilitated glucose transporter), member 4; <i>GK</i>: glycerol kinase; <i>ACLY</i>: ATP citrate lyase; <i>ACAC</i>: acetyl-CoA carboxylase; <i>FASN</i>: fatty acid synthase; <i>SCD</i>: stearoyl-CoA desaturase (delta-9-desaturase); <i>GPAT2</i>: glycerol-3-phosphate acyltransferase 2, mitochondrial; <i>PDE3</i>: phosphodiesterase 3, cGMP-inhibited; <i>PRKAC</i>: protein kinase, cAMP-dependent, catalytic; <i>HSL</i>: lipase, hormone-sensitive.