A comparison of the responses to the intact pamidronate integrated model with those to the blocked pamidronate integrated model after multi-dose pamidronate administration.

<p>(a) The active osteoclast after multi-dose pamidronate administration. (b) The bone volume after multi-dose pamidronate administration. (c) The MM-cell density after multi-dose pamidronate administration. Blue: the intact model; Black: the blocked model.