Biotin synthesis and transport in bacteria.

<p>The characterized biotin synthesis pathways (A) and the ECF biotin transport mechanism (B) are depicted. Alternative ECF subunit configurations are not shown. Asterisks indicate the presence of a chlamydial homolog based upon genome annotations. The grey dashed box indicates alternative pathways used to synthesize pimeloyl-CoA. Chemical structures were drawn using ChemSketch from ACDLabs.