Immunohistochemical analysis of TDP-43 inclusions, ubiquitin, LC3-I/II, and P62 expression levels in VCP<sup>R155H/R155H</sup> and WT quadriceps.
- Angèle Nalbandian (131106)
- Katrina J. Llewellyn (131108)
- Masashi Kitazawa (131112)
- Hong Z. Yin (131114)
- Mallikarjun Badadani (131116)
- Negar Khanlou (131117)
- Robert Edwards (1230)
- Christopher Nguyen (131119)
- Jogeshwar Mukherjee (131122)
- Tahseen Mozaffar (131124)
- Giles Watts (131125)
- John Weiss (131128)
- Virginia E. Kimonis (131129)
Publication date
September 2012
DOIAbstract
<p>Quadriceps sections revealed increased expression of (A–B) TDP-43, (C–D) ubiquitin, (E–F) LC3-I/II and (G–H) P62 antibodies in VCP<sup>R155H/R155H</sup> mice as compared to their WT littermates (Mag 63×). (I) Western blot analyses confirmed the increased TDP-43, ubiquitin, LC3-I/II and P62 protein expression levels in the VCP<sup>R155H/R155H</sup> mice. Alpha tubulin was used as a loading control.</p
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