<p>H&E staining (upper row) and immunostaining of Bmi1 (lower row) in the wildtype (left) and DDC treated (right) mouse liver tissues. Arrows indicate expanding oval cells. At least 3 animals in each group were assayed.</p
<p>Chow-fed, 10-week-old B6 males were sacrificed after 24-hr fast (Fasted) or following a 24-hr fas...
<p>Granulomatous pathology was more severe in C57BL/6 mice; in contrast, hepatic necrosis (pink) was...
<p><b>A</b> and <b>a</b> show liver sections from NC mice. In infected mice, massive inflammatory ce...
<p>(A) Histopathological analysis of hepatic tissue sections with hematoxylin and eosin staining fro...
<p>(A) Co-IF staining for Cytokeratin-19 (CK19) and Albumin (Alb) (upper panels), E-cadherin and DDB...
<p>H&E staining (A) and A6 and CK19 immunostaining (B) on <i>Bmi1</i> WT and <i>Bmi1</i> KO DDC live...
The biology of progenitor activation in the liver is of considerable medical and scientific interest...
Bmi1 is a polycomb group transcriptional repressor and it has been implicated in regulating self-ren...
<p>(A) H&E staining of liver sections from 4-week old <i>DDB1<sup>F/F</sup></i> and <i>DDB1<sup>F/F<...
Oval cells have great potential for use in cell therapy to treat liver disease, however this cannot ...
<p>A and B: HE staining showing periportal ductular reactions from control (A) and KC depleted rats ...
<p>(A: blank control group; B: model group; C: DECB group; D: positive control group).</p
<p>Histological images of (<b>A</b>) tumor, (<b>B</b>) liver, (<b>C</b>) GI tract and (<b>D</b>) pan...
Liver progenitors, so-called oval cells, proliferate remarkably from periportal areas after severe l...
The pace of research on the potential therapeutic uses of liver stem cells or "oval cells" has accel...
<p>Chow-fed, 10-week-old B6 males were sacrificed after 24-hr fast (Fasted) or following a 24-hr fas...
<p>Granulomatous pathology was more severe in C57BL/6 mice; in contrast, hepatic necrosis (pink) was...
<p><b>A</b> and <b>a</b> show liver sections from NC mice. In infected mice, massive inflammatory ce...
<p>(A) Histopathological analysis of hepatic tissue sections with hematoxylin and eosin staining fro...
<p>(A) Co-IF staining for Cytokeratin-19 (CK19) and Albumin (Alb) (upper panels), E-cadherin and DDB...
<p>H&E staining (A) and A6 and CK19 immunostaining (B) on <i>Bmi1</i> WT and <i>Bmi1</i> KO DDC live...
The biology of progenitor activation in the liver is of considerable medical and scientific interest...
Bmi1 is a polycomb group transcriptional repressor and it has been implicated in regulating self-ren...
<p>(A) H&E staining of liver sections from 4-week old <i>DDB1<sup>F/F</sup></i> and <i>DDB1<sup>F/F<...
Oval cells have great potential for use in cell therapy to treat liver disease, however this cannot ...
<p>A and B: HE staining showing periportal ductular reactions from control (A) and KC depleted rats ...
<p>(A: blank control group; B: model group; C: DECB group; D: positive control group).</p
<p>Histological images of (<b>A</b>) tumor, (<b>B</b>) liver, (<b>C</b>) GI tract and (<b>D</b>) pan...
Liver progenitors, so-called oval cells, proliferate remarkably from periportal areas after severe l...
The pace of research on the potential therapeutic uses of liver stem cells or "oval cells" has accel...
<p>Chow-fed, 10-week-old B6 males were sacrificed after 24-hr fast (Fasted) or following a 24-hr fas...
<p>Granulomatous pathology was more severe in C57BL/6 mice; in contrast, hepatic necrosis (pink) was...
<p><b>A</b> and <b>a</b> show liver sections from NC mice. In infected mice, massive inflammatory ce...