<p>Histograms display the mean of three independent biological replicates ± SD for each species. Chimpanzee cells (S006007) displayed significantly higher caspase-3/7 activity than human cells (AG13153) at 100 nM of staurosporine (Student's t-test, p = 0.023) and at 300 nM of staurosporine (Student's t-test, p = 0.011).</p
<p>Percentage of ATP (representative of cell viability) in 293T-FF (black dots) and A549 (white dots...
were plated in triplicate in 96 well plates overnight and then treated with vehicle (DMSO) or 1 μM s...
<p>(A) Effect of staurosporine treatment on Jurkat cells. Flow cytometry analysis of Jurkat cells st...
<p>Cell viability (resazurin-based TOX-8 assay) was measured after treatment of cells over a range o...
<p>All cell lines were incubated in 96-well plates for 48 h in culture medium supplemented with 100 ...
Previously published gene expression analyses suggested that apoptotic function may be reduced in hu...
<p>Cells treated with MMC for 72 hrs were stained with 10 µg/ml of Hoechst 33342 and visualized unde...
<div><p>Previously published gene expression analyses suggested that apoptotic function may be reduc...
<p>(a) Caspase-3 cleavage after Staurosporine treatment: The left panel shows Caspase-3 cleavage in ...
<p><b>A) Caspase 3 activity</b> in cell lysates from adherent NPCs either left untreated or treated ...
<p>Activity is expressed in relative luminescence units (RLU). Induction of caspase activity is stat...
<p>Activity is expressed in relative luminescence units (RLU). Caspase activity peaks at 24 hr (ANOV...
<p>(A) Activation of caspase-3 was decreased in TCERG1-knockdown Jurkat cells treated with staurospo...
<p>Cells were incubated in the indicated concentrations of staurosporine for 24 hr, fixed, photograp...
<p><b>A</b>. Morphological changes of <i>Xenopus laevis</i> oocytes before (Control) and after 6 hou...
<p>Percentage of ATP (representative of cell viability) in 293T-FF (black dots) and A549 (white dots...
were plated in triplicate in 96 well plates overnight and then treated with vehicle (DMSO) or 1 μM s...
<p>(A) Effect of staurosporine treatment on Jurkat cells. Flow cytometry analysis of Jurkat cells st...
<p>Cell viability (resazurin-based TOX-8 assay) was measured after treatment of cells over a range o...
<p>All cell lines were incubated in 96-well plates for 48 h in culture medium supplemented with 100 ...
Previously published gene expression analyses suggested that apoptotic function may be reduced in hu...
<p>Cells treated with MMC for 72 hrs were stained with 10 µg/ml of Hoechst 33342 and visualized unde...
<div><p>Previously published gene expression analyses suggested that apoptotic function may be reduc...
<p>(a) Caspase-3 cleavage after Staurosporine treatment: The left panel shows Caspase-3 cleavage in ...
<p><b>A) Caspase 3 activity</b> in cell lysates from adherent NPCs either left untreated or treated ...
<p>Activity is expressed in relative luminescence units (RLU). Induction of caspase activity is stat...
<p>Activity is expressed in relative luminescence units (RLU). Caspase activity peaks at 24 hr (ANOV...
<p>(A) Activation of caspase-3 was decreased in TCERG1-knockdown Jurkat cells treated with staurospo...
<p>Cells were incubated in the indicated concentrations of staurosporine for 24 hr, fixed, photograp...
<p><b>A</b>. Morphological changes of <i>Xenopus laevis</i> oocytes before (Control) and after 6 hou...
<p>Percentage of ATP (representative of cell viability) in 293T-FF (black dots) and A549 (white dots...
were plated in triplicate in 96 well plates overnight and then treated with vehicle (DMSO) or 1 μM s...
<p>(A) Effect of staurosporine treatment on Jurkat cells. Flow cytometry analysis of Jurkat cells st...