<p>CFSE labeled splenocytes differentiated under T<sub>H</sub>1, T<sub>H</sub>2, T<sub>H</sub>17, or iT<sub>reg</sub> conditions and treated with vehicle (DMSO), T09 (5 µM), GSK2033 (5 µM), or a combination of T09 and GSK2033 (5 µM each) for the duration of the time course (5 days). Cells were FACS analyzed and gated on live, CD4<sup>+</sup> T cells. (<i>n = 4</i>).</p
<p>(<b>a–d</b>) CD8+ T cell proliferation under various stimuli. Cultures were incubated for 48 hour...
<p>(A) Western blot analysis was performed on WT (+/+) or <i>Lxr</i>αβ<i>−/−</i> MPECs, treated with...
<p>(A) BrdU incorporation after 4 days of TCR stimulation with the indicated treatments. Results are...
<p><i>A</i>, Intracellular cytokine staining on splenocytes differentiated under T<sub>H</sub>1, T<s...
The nuclear receptor Liver X Receptor (LXR) is a ligand-activated transcription factor that has been...
<p>(A) Flow cytometric analysis of the percentage of CD4<sup>hi</sup>CD25<sup>+</sup> regulatory T c...
<p>(A) Flow cytometric analysis of the CFSE signal in CD4<sup>hi</sup>CD25<sup>+</sup> regulatory T ...
<p>Isolated PBMCs were treated with DMSO or 10 µM T0901317 for 24 or 48 hours and CD226, CD244 or CD...
<p><b>A:</b> Primary human monocytes were treated 24 hours with 10 µM T0901317 to perform microarray...
<p>(A) MLR assay: C3H T cells vs. bone marrow-derived DCs. Where indicated, 129 ES-DCs or ES-SCs wer...
<p>A) CFSE-labeled cell CD4<sup>+</sup> T cells were used in the CD4<sup>+</sup> T cell/Huh7.5 co-cu...
<p>Purified monocytes were treated with DMSO or 10 µM T0901317 for 24 or 48 hours and CD226, CD244 o...
<p>(A) Flow cytometric analysis of CD69 expression by CD4<sup>+</sup> splenic T cells isolated 2 wk ...
<p>CFSE labeled CD4<sup>+</sup>CD25<sup>−</sup> cells were co-cultured with different concentration ...
<p>(A) Specific lysis of Ltk<sup>−</sup> target cells (H2<sup>k</sup>) by alloreactive CTLs derived ...
<p>(<b>a–d</b>) CD8+ T cell proliferation under various stimuli. Cultures were incubated for 48 hour...
<p>(A) Western blot analysis was performed on WT (+/+) or <i>Lxr</i>αβ<i>−/−</i> MPECs, treated with...
<p>(A) BrdU incorporation after 4 days of TCR stimulation with the indicated treatments. Results are...
<p><i>A</i>, Intracellular cytokine staining on splenocytes differentiated under T<sub>H</sub>1, T<s...
The nuclear receptor Liver X Receptor (LXR) is a ligand-activated transcription factor that has been...
<p>(A) Flow cytometric analysis of the percentage of CD4<sup>hi</sup>CD25<sup>+</sup> regulatory T c...
<p>(A) Flow cytometric analysis of the CFSE signal in CD4<sup>hi</sup>CD25<sup>+</sup> regulatory T ...
<p>Isolated PBMCs were treated with DMSO or 10 µM T0901317 for 24 or 48 hours and CD226, CD244 or CD...
<p><b>A:</b> Primary human monocytes were treated 24 hours with 10 µM T0901317 to perform microarray...
<p>(A) MLR assay: C3H T cells vs. bone marrow-derived DCs. Where indicated, 129 ES-DCs or ES-SCs wer...
<p>A) CFSE-labeled cell CD4<sup>+</sup> T cells were used in the CD4<sup>+</sup> T cell/Huh7.5 co-cu...
<p>Purified monocytes were treated with DMSO or 10 µM T0901317 for 24 or 48 hours and CD226, CD244 o...
<p>(A) Flow cytometric analysis of CD69 expression by CD4<sup>+</sup> splenic T cells isolated 2 wk ...
<p>CFSE labeled CD4<sup>+</sup>CD25<sup>−</sup> cells were co-cultured with different concentration ...
<p>(A) Specific lysis of Ltk<sup>−</sup> target cells (H2<sup>k</sup>) by alloreactive CTLs derived ...
<p>(<b>a–d</b>) CD8+ T cell proliferation under various stimuli. Cultures were incubated for 48 hour...
<p>(A) Western blot analysis was performed on WT (+/+) or <i>Lxr</i>αβ<i>−/−</i> MPECs, treated with...
<p>(A) BrdU incorporation after 4 days of TCR stimulation with the indicated treatments. Results are...