<p>The graph shows the percent change in sleep (%Δsleep) after 12 h of mechanical sleep deprivation (red), 6 h of sleep recovery (light blue), and 9 h of sleep recovery (dark blue) in <i>inc<sup>f00285</sup></i> (n = 45 females), <i>inc<sup>mw</sup></i> (n = 68 females), and iso31 (n = 41 females) showing that the homeostatic response to sleep loss is disrupted in <i>inc</i> mutants. Error bars are SEM. * p<0.05 with Student's t test.</p
Although it is widely accepted that sleep must serve an essential biological function, little is kno...
Extended periods of waking result in physiological impairments in humans, rats, and flies. Sleep hom...
Although it is widely accepted that sleep must serve an essential biological function, little is kno...
<p>(A) <i>inc</i> mRNA transcript levels are reduced in <i>inc<sup>f00285</sup></i> (n = 4×20 male h...
<p>A) Sleep profiles for the baseline, deprivation and recovery day were plotted against each other ...
<p>(A-C) <i>Nipped-B</i> heterozygous females, but not males, sleep less than <i>w</i><sup><i>iso31<...
<p><b>Sleep homeostatic system was completely preserved in <i>gce</i><sup><i>2</i>.<i>5k</i></sup> f...
<p>(A) Daily time course (30 min interval) of the amount of sleep in 6 to 8 day-old males of control...
Sleep rebound—the increase in sleep that follows sleep deprivation (SD)—is a hallmark of homeostatic...
Sleep rebound – the increase in sleep that follows sleep deprivation (SD) – is a hallmark of homeost...
<p>A) Averaged sleep profiles of control <i>iso31</i> (black) and <i>Nf1</i><sup><i>P1/P2</i></sup> ...
<p>(A) Western blot shows results of an α-V5 immunoprecipitation from S2 cell supernatant transfecte...
Background and Study Objectives:Flies mutant for the canonical clock protein cycle (cyc01) exhibit a...
<p>Sleep parameters of control and mutants flies under control conditions (flies fed with gelatin so...
<p>(A) Average sleep bout length (ABL), (B) total number of sleep bouts, (C) latency to sleep after ...
Although it is widely accepted that sleep must serve an essential biological function, little is kno...
Extended periods of waking result in physiological impairments in humans, rats, and flies. Sleep hom...
Although it is widely accepted that sleep must serve an essential biological function, little is kno...
<p>(A) <i>inc</i> mRNA transcript levels are reduced in <i>inc<sup>f00285</sup></i> (n = 4×20 male h...
<p>A) Sleep profiles for the baseline, deprivation and recovery day were plotted against each other ...
<p>(A-C) <i>Nipped-B</i> heterozygous females, but not males, sleep less than <i>w</i><sup><i>iso31<...
<p><b>Sleep homeostatic system was completely preserved in <i>gce</i><sup><i>2</i>.<i>5k</i></sup> f...
<p>(A) Daily time course (30 min interval) of the amount of sleep in 6 to 8 day-old males of control...
Sleep rebound—the increase in sleep that follows sleep deprivation (SD)—is a hallmark of homeostatic...
Sleep rebound – the increase in sleep that follows sleep deprivation (SD) – is a hallmark of homeost...
<p>A) Averaged sleep profiles of control <i>iso31</i> (black) and <i>Nf1</i><sup><i>P1/P2</i></sup> ...
<p>(A) Western blot shows results of an α-V5 immunoprecipitation from S2 cell supernatant transfecte...
Background and Study Objectives:Flies mutant for the canonical clock protein cycle (cyc01) exhibit a...
<p>Sleep parameters of control and mutants flies under control conditions (flies fed with gelatin so...
<p>(A) Average sleep bout length (ABL), (B) total number of sleep bouts, (C) latency to sleep after ...
Although it is widely accepted that sleep must serve an essential biological function, little is kno...
Extended periods of waking result in physiological impairments in humans, rats, and flies. Sleep hom...
Although it is widely accepted that sleep must serve an essential biological function, little is kno...