<p>GBS strains NCTC 10/84 (A) and COH31 (B) were compared with their Δ<i>srr1</i> variants (Δ<i>srr1</i>) for binding to MalE:Aα<sub>198–282</sub> or MalE:Aα<sub>283–410</sub>. Values are mean ± S.D. percent of WT GBS binding to immobilized MalE:Aα<sub>283–410</sub>. * = P<0.01.</p
<p>GAGs bind neutral hydrogen bond donors on the protein that possess significantly high G<sub>ES</s...
<p>(<b>A-C</b>) fH binding to wild type and modified Ghfp and fHbp V3.45 was assessed by far Western...
<p>A. Adherence to hBMEC by WT and mutant strains (MOI = 1). B. Invasion of hBMEC by WT and mutant s...
<p>(A) GBS strains COH31 (left) and NCTC 10/84 (right) were compared with their Δ<i>srr1</i> variant...
<p>(A) Binding of <sub>FLAG</sub>Srr1-BR and <sub>FLAG</sub>Srr1-BRΔlatch proteins to immobilized fi...
<p>Flat bottomed 96-well polystyrene plates were coated with 21 nM human fibrinogen and 5×10<sup>6</...
<p>Flat bottomed 96-well polystyrene plates were coated with 21 nM human fibrinogen and 5×10<sup>6</...
<p>(A) Fibrinogen on the surface of hBMEC pretreated with or without exogenous fibrinogen (Fg; 20 µg...
<p>(A) Alignment of Srr1 binding domain in the human fibrinogen Aα chain, with the homologous region...
<p>(A) Fold change in transcription levels of <i>fbsA</i> (filled boxes) and <i>fbsB</i> (open boxes...
Obiective: The ability to bind fibrinogen (Fng) is a virulence determinant for a diverse group of ba...
Binding of Tp0136-expressing B314 to wells coated with human tissue fibronectin was significantly hi...
<p>Strains of the M types indicated were analyzed for ability to bind radiolabelled C4BP. Upper pane...
International audienceAnalyses of site-directed fibrinogen mutants expressed in several recombinant ...
<p>A. FITC-fibrinogen binding to cells expressing αVβ3 in the presence of 1 mM Ca<sup>2+</sup> and 1...
<p>GAGs bind neutral hydrogen bond donors on the protein that possess significantly high G<sub>ES</s...
<p>(<b>A-C</b>) fH binding to wild type and modified Ghfp and fHbp V3.45 was assessed by far Western...
<p>A. Adherence to hBMEC by WT and mutant strains (MOI = 1). B. Invasion of hBMEC by WT and mutant s...
<p>(A) GBS strains COH31 (left) and NCTC 10/84 (right) were compared with their Δ<i>srr1</i> variant...
<p>(A) Binding of <sub>FLAG</sub>Srr1-BR and <sub>FLAG</sub>Srr1-BRΔlatch proteins to immobilized fi...
<p>Flat bottomed 96-well polystyrene plates were coated with 21 nM human fibrinogen and 5×10<sup>6</...
<p>Flat bottomed 96-well polystyrene plates were coated with 21 nM human fibrinogen and 5×10<sup>6</...
<p>(A) Fibrinogen on the surface of hBMEC pretreated with or without exogenous fibrinogen (Fg; 20 µg...
<p>(A) Alignment of Srr1 binding domain in the human fibrinogen Aα chain, with the homologous region...
<p>(A) Fold change in transcription levels of <i>fbsA</i> (filled boxes) and <i>fbsB</i> (open boxes...
Obiective: The ability to bind fibrinogen (Fng) is a virulence determinant for a diverse group of ba...
Binding of Tp0136-expressing B314 to wells coated with human tissue fibronectin was significantly hi...
<p>Strains of the M types indicated were analyzed for ability to bind radiolabelled C4BP. Upper pane...
International audienceAnalyses of site-directed fibrinogen mutants expressed in several recombinant ...
<p>A. FITC-fibrinogen binding to cells expressing αVβ3 in the presence of 1 mM Ca<sup>2+</sup> and 1...
<p>GAGs bind neutral hydrogen bond donors on the protein that possess significantly high G<sub>ES</s...
<p>(<b>A-C</b>) fH binding to wild type and modified Ghfp and fHbp V3.45 was assessed by far Western...
<p>A. Adherence to hBMEC by WT and mutant strains (MOI = 1). B. Invasion of hBMEC by WT and mutant s...
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