Functional analysis of proteins enriched in the human PSD.

<p><b>a.</b> Ontology hierarchical tree leading to the Biological Process ‘Cellular Component Morphogenesis’. In red are the terms significantly enriched in proteins abundant in the human PSD. <b>b.</b> Molecular interaction map of proteins from the human PSD that belong to the Biological Process ‘Cellular Component Morphogenesis’ (CCM) or are known to be involved in semaphorin signaling. Only CCM proteins enriched in the human PSD are considered. Some proteins related to semaphorin signaling are not enriched in either species, these are identified with a white name. Proteins highly interconnected are represented in clusters of different colors. Clustering was done using the Markov Clustering Algorithm (MCL) in BioLayout Express 3D <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046683#pone.0046683-Jensen1" target="_blank">[24]</a>. Node edges are coloured according to a confidence score, from red (100% confidence) to blue (40% confidence).