Genetic structure of penicillinase plasmid pPM1 and its segregant.

<p>In A, pPM1 structure is shown. Inner circle indicates homologous regions to <i>S. aureus</i> plasmid SAP014A (GenBank accession number GQ900379), SAP063A (GenBank accession number GQ900418), and pSK156 (GenBank accession number GQ900448). The IS<i>431</i> region with the transposase gene (<i>tnp</i>) is shaded in light green. A Greek delta symbol indicates truncated coding sequence. In B, a segregant of pPM1 in MES<i>_tet</i> locus is shown. Tet^r, tetracycline-resistant; Tet^s, tetracycline-susceptible.