<p>(A). Domain structure of FUS with the C-terminal NLS. The ALS mutations are clustered in the NLS and the mutations studied here are shown in red. (B) Amino acid sequence alignments of FUS-NLS with other PY NLS’s from hnRNP A1, hnRNP D, hnRNP M and TAP. (C). Sequence alignment of FUS-NLS from different organisms.</p
Mutations in the FUS gene have recently been described as a cause of familial amyotrophic lateral sc...
Abstract Mutations in the FUS gene have recently been described as a cause of familial amyotrophic ...
The C-terminal nuclear localization sequence of FUsed in Sarcoma (FUS-NLS) is critical for its nucle...
Mutations in the nuclear RNA-binding protein Fused in Sarcoma (FUS) gene are responsible for 5% of i...
<p>(A) Sequence alignment and motif prediction using PSORT II identified NLS1 sequence among ortholo...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakne...
Aggregations of fused in sarcoma (FUS), a multifunctional RNA processing protein, define a pathologi...
<p>(A) The solid straight line indicated the major domains or binding regions predicted by SMART pro...
The C-terminal nuclear localization sequence of FUsed in Sarcoma (FUS-NLS) is critical for its nucle...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakne...
<p>Fused in sarcoma (FUS) gene encodes the RNA binding protein FUS. This gene is mapped to chromosom...
<p>ClustalW amino acid sequence alignment for FslE (FTT0025c), FupA (FTT0918), FupB (FTT0919), FmvA ...
<p><b>(A)</b> Phylogram showing orthologous FKBP12 proteins from Human (HsFKBP12), <i>S</i>. <i>cere...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakne...
<p>A) Confocal fluorescent microscopy showing the cellular localization of EGFP-FUS mutants in HEK29...
Mutations in the FUS gene have recently been described as a cause of familial amyotrophic lateral sc...
Abstract Mutations in the FUS gene have recently been described as a cause of familial amyotrophic ...
The C-terminal nuclear localization sequence of FUsed in Sarcoma (FUS-NLS) is critical for its nucle...
Mutations in the nuclear RNA-binding protein Fused in Sarcoma (FUS) gene are responsible for 5% of i...
<p>(A) Sequence alignment and motif prediction using PSORT II identified NLS1 sequence among ortholo...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakne...
Aggregations of fused in sarcoma (FUS), a multifunctional RNA processing protein, define a pathologi...
<p>(A) The solid straight line indicated the major domains or binding regions predicted by SMART pro...
The C-terminal nuclear localization sequence of FUsed in Sarcoma (FUS-NLS) is critical for its nucle...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakne...
<p>Fused in sarcoma (FUS) gene encodes the RNA binding protein FUS. This gene is mapped to chromosom...
<p>ClustalW amino acid sequence alignment for FslE (FTT0025c), FupA (FTT0918), FupB (FTT0919), FmvA ...
<p><b>(A)</b> Phylogram showing orthologous FKBP12 proteins from Human (HsFKBP12), <i>S</i>. <i>cere...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakne...
<p>A) Confocal fluorescent microscopy showing the cellular localization of EGFP-FUS mutants in HEK29...
Mutations in the FUS gene have recently been described as a cause of familial amyotrophic lateral sc...
Abstract Mutations in the FUS gene have recently been described as a cause of familial amyotrophic ...
The C-terminal nuclear localization sequence of FUsed in Sarcoma (FUS-NLS) is critical for its nucle...