Random effect model of Log hazard ratio (LogHR) with 95% confidence interval for studies comparing the effect of <i>BRAF-</i>V600E mutation on overall survival in melanoma patients.

<p>A LogHR <0 implies a survival benefit for patients with <i>BRAF</i> mutation. The square size indicates the power of each study in meta-analysis based on the number of patients in that study. The center of diamond shape at the lowest part indicates the combined LogHR for meta-analysis and its extremities the 95% confidence interval.