Pathway analysis of WGS and RNAseq results.
- Winnie S. Liang (105564)
- David W. Craig (128068)
- John Carpten (117061)
- Mitesh J. Borad (128074)
- Michael J. Demeure (128078)
- Glen J. Weiss (128085)
- Tyler Izatt (128091)
- Shripad Sinari (128099)
- Alexis Christoforides (128104)
- Jessica Aldrich (128110)
- Ahmet Kurdoglu (128116)
- Michael Barrett (128123)
- Lori Phillips (128126)
- Hollie Benson (128130)
- Waibhav Tembe (117037)
- Esteban Braggio (128134)
- Jeffrey A. Kiefer (128138)
- Christophe Legendre (117048)
- Richard Posner (128144)
- Galen H. Hostetter (128150)
- Angela Baker (128155)
- Jan B. Egan (128161)
- Haiyong Han (128169)
- Douglas Lake (128175)
- Edward C. Stites (128180)
- Ramesh K. Ramanathan (128184)
- Rafael Fonseca (128188)
- A. Keith Stewart (128191)
- Daniel Von Hoff (117063)
Publication date
October 2012
DOIAbstract
<p>Whole genome and RNAseq data were integrated and analyzed using GeneGo's Metaminer Pancreatic Cancer Disease module to identify pathways that may be affected by mutations and/or significant expression changes (q-value<0.05, corrected). The top pathways (minimum mapping p-value across all WGS and RNAseq datasets <0.05) are summarized based off of GeneGo maps. Breakdown of affected pathways in each patient are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0043192#pone.0043192.s005" target="_blank">Table S4</a>.</p
Add to ORKG