Comparison of mutation rates between immuno-active and inactive regions of the preC/C region.

a<p>P-values were determined by a comparison with the mutation rate of immuno-inactive regions.</p>b<p>N.S: Not significant.</p>c<p>Statistically significant after a Bonferroni post hoc analysis (p<0.05).</p><p>Immuno-active regions include MHC class I-restricted epitopes, MHC class II-restricted epitopes, and the 81–105 region of MHC class II.