<p>orange: sweep from standing variation blue: sweep from a new mutation, blue: neutral model a: A cartoon of the allele frequency trajectory with relevant parameters: <i>f</i><sub>1</sub>: allele frequency at the time selection started, <i>f</i><sub>cur</sub>: allele frequency at the time mutation is observed. <i>t</i><sub>1</sub>: time at which selection started. <i>t</i><sub>0</sub>: time when mutation arose.,. b: 100 stochastic realizations of the allele frequency trajectory. Panels c,d: Age distribution of an allele at 1% frequency and 5% frequency in a population (log scale). Blue line denotes neutrality, green lines represent selection with α = 20,100,200 and 1000 (right to left). Panels e,f: Distribution of the EHH (e) and H (f) sta...
Polymorphism data can be used to identify loci at which a beneficial allele has recently gone to fix...
<div> <div> <div> <p>Understanding the genetic basis of phenotypic adaptation to changing environmen...
123 pagesA selective sweep happens when an adaptive allele increases in frequency and spreads throug...
A) Time to reach new trait optimum B) Rate of change in phenotype C) Genetic variance after 0.1 × Na...
A) Speed of fixation of selective sweep mutations. B) Dynamics of fixations that occur after the new...
<p>The number of origins of adaptive mutations on unique haplotype backgrounds was measured in simul...
An outstanding question in human genetics has been the degree to which adaptation occurs from standi...
An outstanding question in human genetics has been the degree to which adaptation occurs from standi...
Distribution of (A) starting frequencies and (B) selection coefficients (s) of the selected alleles....
<p>This cartoon depicts a population of ten chromosomes, subject to recurrent selective sweeps (RSS)...
<p><b>(A)</b> Example single-locus model. A single allele, denoted 1 (red) at driver locus is consi...
<p>(A) Simulated trajectory of a neutral allele affected by recurrent selective sweeps, from its ori...
<p>Circles represent individuals in the population; the different patterns indicate independent hapl...
<p>Panels in the upper row show averaged allele frequency dynamics over 25 generations after an alle...
ABSTRACT We model selection at a locus affecting a quantitative trait (QTL) in the presence of genet...
Polymorphism data can be used to identify loci at which a beneficial allele has recently gone to fix...
<div> <div> <div> <p>Understanding the genetic basis of phenotypic adaptation to changing environmen...
123 pagesA selective sweep happens when an adaptive allele increases in frequency and spreads throug...
A) Time to reach new trait optimum B) Rate of change in phenotype C) Genetic variance after 0.1 × Na...
A) Speed of fixation of selective sweep mutations. B) Dynamics of fixations that occur after the new...
<p>The number of origins of adaptive mutations on unique haplotype backgrounds was measured in simul...
An outstanding question in human genetics has been the degree to which adaptation occurs from standi...
An outstanding question in human genetics has been the degree to which adaptation occurs from standi...
Distribution of (A) starting frequencies and (B) selection coefficients (s) of the selected alleles....
<p>This cartoon depicts a population of ten chromosomes, subject to recurrent selective sweeps (RSS)...
<p><b>(A)</b> Example single-locus model. A single allele, denoted 1 (red) at driver locus is consi...
<p>(A) Simulated trajectory of a neutral allele affected by recurrent selective sweeps, from its ori...
<p>Circles represent individuals in the population; the different patterns indicate independent hapl...
<p>Panels in the upper row show averaged allele frequency dynamics over 25 generations after an alle...
ABSTRACT We model selection at a locus affecting a quantitative trait (QTL) in the presence of genet...
Polymorphism data can be used to identify loci at which a beneficial allele has recently gone to fix...
<div> <div> <div> <p>Understanding the genetic basis of phenotypic adaptation to changing environmen...
123 pagesA selective sweep happens when an adaptive allele increases in frequency and spreads throug...