Relationship between gene expression levels and mRNA decay rates across individuals.

<p>A. QQ-plot of the t-statistics for association between steady-state expression levels and decay rates across individuals (y-axis) compared to the null distribution of t-statistics assessed by permutations (x-axis). The sign of the t-statistic indicates the direction of correlation. Genes with concordant relationships (orange) have negative t-statistics and genes with discordant relationships (purple) have positive t-statistics. B. Density distributions of the Pearson correlations (x-axis) between mRNA decay rates and PolII reads for genes with either concordant (orange) or discordant (purple) relationships between decay rates and steady-state expression levels across individuals.